5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid

5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid - Names and Identifiers

Name	5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid
Synonyms	5-Chloro-4-(trifluoroMethyl)picolinic acid 5-chloro-4-(trifluoromethyl)picolinic acid 5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid 5-Chloro-4-(trifluoroMethyl)-2-pyridinecarboxylic acid 5-Chloro-4-(trifluoromethyl)-2-pyridinecarboxylic acid 2-Pyridinecarboxylic acid, 5-chloro-4-(trifluoromethyl)-
CAS	796090-31-8
EINECS	937-991-2
InChI	InChI=1S/C7H3ClF3NO2/c8-4-2-12-5(6(13)14)1-3(4)7(9,10)11/h1-2H,(H,13,14)

5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C7H3ClF3NO2
Molar Mass	225.55
Density	1.603±0.06 g/cm3(Predicted)
Boling Point	322.4±42.0 °C(Predicted)
pKa	2.98±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid - Introduction

5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid(5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid) is an organic compound. Its chemical formula is C7H3ClF3NO2 and its relative molecular mass is 211.55g/mol. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White to light yellow crystalline
-Melting point: 154-156°C
-Boiling point: 318°C
-Good stability at room temperature
-Insoluble in water, soluble in organic solvents such as alcohols and ketones

Use:
- 5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid is often used in organic synthesis reactions as an important synthetic intermediate
-Can be used to prepare pesticides, pharmaceuticals and optical materials

Preparation Method:
5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid can be prepared in a variety of ways. One common method is to react 5-chloro -2-formyl pyridine () with trifluoromethyl acid (trifluoromethanesulfonic acid) to generate an intermediate, and then carry out subsequent reactions to obtain the target product.

Safety Information:
- 5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid is not obviously dangerous and irritating under normal use conditions, but it is still necessary to follow general laboratory practices and take necessary protective measures.
-Avoid contact with substances such as strong oxidants and strong acids during storage and handling.
-During use, ensure that the room is well ventilated and use appropriate personal protective equipment, such as lab gloves and eye protection.
-If you accidentally come into contact with 5-Chloro-4-(trifluoromethyl)pyridine-2-carboxylic acid, rinse immediately with plenty of water and seek medical assistance.

Last Update：2024-04-09 02:00:48